The Impact of VEGF Inhibition on Clinical Outcomes in Patients With Advanced Non-Small Cell Lung Cancer Treated With Immunotherapy: A Retrospective Cohort Study

BackgroundIn recent years, immune checkpoint inhibitors (ICIs) in combination with chemotherapy have increased survival in patients with advanced non-small cell lung cancer (NSCLC). Vascular endothelial growth factor (VEGF), which plays a key role in tumor angiogenesis, is an immunological modulator...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Keiko Tanimura, Tadaaki Yamada, Ayaka Omura, Shinsuke Shiotsu, Nobutaka Kataoka, Takayuki Takeda, Ryusuke Taniguchi, Takahiro Yamada, Mayumi Takeuchi, Yusuke Chihara, Yoshie Morimoto, Masahiro Iwasaku, Yoshiko Kaneko, Junji Uchino, Koichi Takayama
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-05-01
Subjects:	immune checkpoint inhibitors immunotherapy anti-VEGF therapy non-small cell lung cancer treatment response
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2021.663612/full