Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection.

Blocking Plasmodium, the causative agent of malaria, at the asymptomatic pre-erythrocytic stage would abrogate disease pathology and prevent transmission. However, the lack of well-defined features within vaccine-elicited antibody responses that correlate with protection represents a major roadblock...

Full description

Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Ganesh Ram R Visweswaran, Kamalakannan Vijayan, Ramyavardhanee Chandrasekaran, Olesya Trakhimets, Samantha L Brown, Vladimir Vigdorovich, Ashton Yang, Andrew Raappana, Alex Watson, William Selman, Meghan Zuck, Nicholas Dambrauskas, Alexis Kaushansky, D Noah Sather
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2022-07-01
Online Access:	https://doi.org/10.1371/journal.ppat.1010671