Quantitative analysis of drug–drug interactions among active components of Xuebijing in inhibiting LPS-induced TLR4 signaling and NO production

Abstract Despite the long history of Traditional Chinese Medicine (TCM) in disease treatment, the underlying “Jun–Chen–Zuo–Shi” principle remains largely unexplored. To address this gap, it is essential to elucidate the interactions between active substances in TCM through quantitative molecular and...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Tianshu Zhang, Hongyuan Li, Cong Lin, Xiaohui Wang
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-04-01
Subjects:	Xuebijing Traditional Chinese medicine Toll-like receptor 4 Chou–Talalay method Drug combination Nitric oxide
Online Access:	https://doi.org/10.1038/s41598-025-95994-9