The Dual Dose-Dependent Effects of Corticosterone on Hippocampal Cell Apoptosis After Traumatic Brain Injury Depend on the Activation Ratio of Mineralocorticoid Receptors to Glucocorticoid Receptors

In our recent studies, we reported that mineralocorticoid receptor (MR) had the opposite effects of glucocorticoid receptor (GR) on neural cell survival after traumatic brain injury (TBI). However, whether short-term use of high-dose natural glucocorticoids, which are mixed agonists of both MR and G...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Pharmacology
المؤلفون الرئيسيون: Bin Zhang, Mengshi Yang, Qiongyu Yan, Xiaojian Xu, Fei Niu, Jinqian Dong, Yuan Zhuang, Shenghua Lu, Qianqian Ge, Baiyun Liu
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2021-07-01
الموضوعات:
traumatic brain injury
corticosterone
mineralocorticoid receptor
glucocorticoid receptor
apoptosis
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fphar.2021.713715/full

الانترنت

https://www.frontiersin.org/articles/10.3389/fphar.2021.713715/full

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