Oxidant-free cross-dehydrogenative oxyalkylation enables late-stage functionalization of drugs

Late-stage functionalization is an attractive strategy that allows chemists to bypass lengthy synthetic processes, facilitating the rapid generation of drug analogs with potentially enhanced pharmacokinetic and pharmacological properties. This study describes a novel approach for cross-dehydrogenati...

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發表在:	The Innovation
Main Authors:	Weiqiu Liang, Jiahao Li, Jianbin Li, Chengda Wu, Zhiyu Tu, Bo-Shuai Mu, Yang Xu, Longlong Song, Mengxin Xu, Xi-Yang Cui, Chao-Jun Li, Zhibo Liu
格式:	Article
語言:	英语
出版:	Elsevier 2025-04-01
主題:	ionizing radiation minisci reaction late-stage functionalization
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2666675825000128