Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment

Abstract Background Pancreatic cancer is one of the most lethal type of cancers, with an overall five-year survival rate of less than 5%. It is usually diagnosed at an advanced stage with limited therapeutic options. To date, no effective treatment options have demonstrated long-term benefits in adv...

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Bibliographic Details
Published in:Journal of Experimental & Clinical Cancer Research
Main Authors: Chin-King Looi, Felicia Fei-Lei Chung, Chee-Onn Leong, Shew-Fung Wong, Rozita Rosli, Chun-Wai Mai
Format: Article
Language:English
Published: BMC 2019-04-01
Subjects:
Pancreatic cancer
Immunotherapy
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s13046-019-1153-8

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http://link.springer.com/article/10.1186/s13046-019-1153-8

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