The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and oral commensalism

ABSTRACT Candida albicans is a diploid human fungal pathogen that displays significant genomic and phenotypic heterogeneity over a range of virulence traits and in the context of a variety of environmental niches. Here, we show that the effect of Rob1 on biofilm and filamentation virulence traits is...

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Bibliographic Details

Published in:	mBio
Main Authors:	Virginia E. Glazier, Juraj Kramara, Tomye Ollinger, Norma V. Solis, Robert Zarnowski, Rohan S. Wakade, Min-Ju Kim, Gabriel J. Weigel, Shen-Huan Liang, Richard J. Bennett, Melanie Wellington, David R. Andes, Mark A. Stamnes, Scott G. Filler, Damian J. Krysan
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-10-01
Subjects:	Candida albicans biofilms filamentation virulence
Online Access:	https://journals.asm.org/doi/10.1128/mbio.01521-23