Hyperoxia but not high tidal volume contributes to ventilator-induced lung injury in healthy mice

Abstract Background Mechanical ventilation is a supportive therapy used to maintain respiratory function in several clinical and surgical cases but is always accompanied by lung injury risk due to improper treatment. We investigated how tidal volume and oxygen delivery would contribute independently...

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出版年:	BMC Pulmonary Medicine
主要な著者:	Yong Xu, Yu Li, Da Zhai, Chen Yan, Jingyan Liang, Taiga Ichinomiya, Tetsuya Hara, Chiaki Inadomi, Tao-Sheng Li
フォーマット:	論文
言語:	英語
出版事項:	BMC 2023-09-01
主題:	Mechanical ventilation Tidal volume Oxidative damage Inflammatory response Mechanotransduction
オンライン･アクセス:	https://doi.org/10.1186/s12890-023-02626-x