Unraveling the Protective Role of Oleocanthal and Its Oxidation Product, Oleocanthalic Acid, against Neuroinflammation

Neuroinflammation is a critical aspect of various neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases. This study investigates the anti-neuroinflammatory properties of oleocanthal and its oxidation product, oleocanthalic acid, using the BV-2 cell line activated with lipopolysacc...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Maria Cristina Barbalace, Michela Freschi, Irene Rinaldi, Lorenzo Zallocco, Marco Malaguti, Clementina Manera, Gabriella Ortore, Mariachiara Zuccarini, Maurizio Ronci, Doretta Cuffaro, Marco Macchia, Silvana Hrelia, Laura Giusti, Maria Digiacomo, Cristina Angeloni
Format:	Article
Language:	English
Published:	MDPI AG 2024-09-01
Subjects:	oleocanthal oleocanthalic acid neuroinflammation BV-2 microglial cells lipopolysaccharide TLR4
Online Access:	https://www.mdpi.com/2076-3921/13/9/1074