Transcription factor 25 modulates gametocytogenesis and ribosome biogenesis in the malaria parasite Plasmodium falciparum

IntroductionPlasmodium falciparum, the causative agent of severe malaria, predominantly reproduces through asexual stages within human red blood cells, with a small subset differentiating into transmissible gametocytes. TCF25 is recognized in other eukaryotes as a protein with dual roles: a transcri...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Jing Wu, Zuping Zhang, Chandara Ngim, Wenyu Yang, Peiyi Li, Fei Wang, Jingru Ye, Bo Li, Bin Tian, Qingfeng Zhang, Xiaomin Shang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	Plasmodium falciparum gametocytogenesis transcription factor 25 rRNA ribosome biogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1652542/full