Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study

Introduction Identifying an underlying germline cancer predisposition (CP) in a child with cancer has potentially significant implications for both the child and biological relatives. Cohort studies indicate that 10%–15% of paediatric cancer patients carry germline pathogenic or likely pathogenic va...

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Bibliographic Details

Published in:	BMJ Open
Main Authors:	Yuyan Chen, Mark Pinese, Claire Wakefield, Frank Alvaro, Katherine Tucker, Tracey A O’Brien, Vanessa J Tyrrell, Judy Kirk, Kate Hetherington, Eliza Courtney, Kristine Barlow-Stewart, Noemi Auxiliadora Fuentes Bolanos, Bhavna Padhye, Macabe Daley, Jacqueline Hunter, Meera Warby, Sarah Josephi-Taylor, Marie Wong-Erasmus, Paulette Barahona, Pamela Ajuyah, Ann-Kristin Altekoester, Loretta M S Lau, Dianne Sylvester, Luciano Dalla Pozza
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2023-05-01
Online Access:	https://bmjopen.bmj.com/content/13/5/e070082.full