Systematic spatial bias in DNA microarray hybridization is caused by probe spot position-dependent variability in lateral diffusion.

<h4>Background</h4>The hybridization of nucleic acid targets with surface-immobilized probes is a widely used assay for the parallel detection of multiple targets in medical and biological research. Despite its widespread application, DNA microarray technology still suffers from several...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	PLoS ONE
المؤلفون الرئيسيون:	Doris Steger, David Berry, Susanne Haider, Matthias Horn, Michael Wagner, Roman Stocker, Alexander Loy
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Public Library of Science (PLoS) 2011-01-01
الوصول للمادة أونلاين:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023727&type=printable