Low-dose vs. standard-dose alteplase for acute ischemic stroke: a real-world single-center retrospective study

ObjectivesTo investigate the real-world usage patterns and clinical outcomes of low-dose (0.6 mg/kg) versus standard-dose (0.9 mg/kg) intravenous alteplase in patients with acute ischemic stroke (AIS).MethodsThis single-center retrospective study included 707 patients with AIS who received intraveno...

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Bibliographic Details

Published in:	Frontiers in Neurology
Main Authors:	Xin-Lei Mao, Si-Si He, Ya-Xi Zhang, Cai-Dan Lin, Xin-Xin Chen, Shi-Zheng Zhang, Li-Na Ge, Qing-Qing Zhuang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	acute ischemic stroke alteplase low-dose standard-dose real-world study
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1651307/full