Comparative Antiviral Activity of Remdesivir and Anti-HIV Nucleoside Analogs against Human Coronavirus 229E (HCoV-229E)
Remdesivir is a nucleotide prodrug that is currently undergoing extensive clinical trials for the treatment of COVID-19. The prodrug is metabolized to its active triphosphate form and interferes with the action of RNA-dependent RNA polymerase of SARS-COV-2. Herein, we report the antiviral activity o...
| 發表在: | Molecules |
|---|---|
| Main Authors: | , , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
MDPI AG
2020-05-01
|
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/1420-3049/25/10/2343 |