Targeting Bacterial Dsb Proteins for the Development of Anti-Virulence Agents

Recent years have witnessed a dramatic increase in bacterial antimicrobial resistance and a decline in the development of novel antibiotics. New therapeutic strategies are urgently needed to combat the growing threat posed by multidrug resistant bacterial infections. The Dsb disulfide bond forming p...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Roxanne P. Smith, Jason J. Paxman, Martin J. Scanlon, Begoña Heras
Format:	Article
Language:	English
Published:	MDPI AG 2016-07-01
Subjects:	disulfide catalysis DsbA inhibitors DsbB inhibitors anti-virulence fragment-based drug design, antimicrobial resistance
Online Access:	http://www.mdpi.com/1420-3049/21/7/811