Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells.

Forkhead box M1 (FOXM1) is a proliferation-associated transcription factor essential for cell cycle progression. Numerous studies have documented that FOXM1 has multiple functions in tumorigenesis and its elevated levels are frequently associated with cancer progression. Here, we characterized the r...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Gabriel T M Lok, David W Chan, Vincent W S Liu, Winnie W Y Hui, Thomas H Y Leung, K M Yao, Hextan Y S Ngan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Online Access:http://europepmc.org/articles/PMC3157468?pdf=render