Designing a smallpox B-cell and T-cell multi-epitope subunit vaccine using a comprehensive immunoinformatics approach

ABSTRACT Smallpox is a highly contagious human disease caused by the variola virus. Although the disease was eliminated in 1979 due to its highly contagious nature and historical pathogenicity, with a mortality rate of up to 30%, this virus is an important candidate for biological weapons. Currently...

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Bibliographic Details
Published in:Microbiology Spectrum
Main Authors: Changqing Yu, Qi Wu, Jiuqing Xin, Qiujuan Yu, Zhixin Ma, Mengzhou Xue, Qingyuan Xu, Chunfu Zheng
Format: Article
Language:English
Published: American Society for Microbiology 2024-06-01
Subjects:
smallpox
variola virus
vaccine design
multi-epitopes vaccine
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00465-24

Internet

https://journals.asm.org/doi/10.1128/spectrum.00465-24

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