The Strategies and Mechanisms of Immune Checkpoint Inhibitors for Brain Metastases in NSCLC

Brain metastases are more and more common among patients with non-small cell lung cancer (NSCLC). TKI therapy could provide ideal outcomes for patients harboring epidermal growth factor receptor or ALK mutations. For wild-type patients, however, survival is poor because there are few effective treat...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Ji Li, Min Wang, Shuhui Xu, Yuying Li, Jiatong Li, Jinming Yu, Hui Zhu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Subjects:	NSCLC brain metastasis immune checkpoint inhibitors irAEs mechanisms
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.841623/full