Single-cell transcriptome profiling reveals dynamic cell populations and immune infiltration in cerebral cavernous malformation

IntroductionThe cellular subpopulations and signaling pathways in the pathological tissues of cerebral cavernous malformation (CCM) remain incompletely understood. To gain a deeper understanding of the pathogenesis of CCM, we aimed to comprehensively map the cellular subpopulations and signaling pat...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Zhiguang Han, Chengxu Lei, Zhenyu Zhou, Yutong Liu, Yuanli Zhao, Shihao He
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	cerebral cavernous malformation single-cell RNA sequencing multiplex fluorescent immunohistochemistry cell populations immune infiltration
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1592343/full