A tool for evaluating heterogeneity in avidity of polyclonal antibodies

Diversity in specificity of polyclonal antibody (pAb) responses is extensively investigated in vaccine efficacy or immunological evaluations, but the heterogeneity in antibody avidity is rarely probed as convenient tools are lacking. Here we have developed a polyclonal antibodies avidity resolution...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Kan Li, Michael Dodds, Rachel L. Spreng, Milite Abraha, Richard H. C. Huntwork, Lindsay C. Dahora, Tinashe Nyanhete, Sheetij Dutta, Ulrike Wille-Reece, Erik Jongert, Katie J. Ewer, Adrian V. S. Hill, Celina Jin, Jennifer Hill, Andrew J. Pollard, S. Munir Alam, Georgia D. Tomaras, S. Moses Dennison
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Subjects:
dissociation rate
avidity
binning
polyclonal antibodies
Typhim
RTS,S/AS01
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1049673/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1049673/full

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