Interplay between MAPK signaling pathway and autophagy in skin aging: mechanistic insights and therapeutic implications

Skin aging manifests as structural degradation, functional decline, and heightened disease susceptibility. Central to this process is the overactivation of the mitogen-activated protein kinase (MAPK) signaling pathway triggered by reactive oxygen species (ROS). Autophagy, a lysosomal degradation mec...

Full description

Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Xu Liu, Bo Chen, Xuefeng Liu, Xiaoqing Zhang, Jingdong Wu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	skin aging MAPK autophagy interplay natural bioactive compounds
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1625357/full