LncRNA WAC-AS1 promotes osteosarcoma Metastasis and stemness by sponging miR-5047 to upregulate SOX2

Abstract Cancer stemness and osteosarcoma (OS) malignant progression are closely associated. However, the molecular mechanisms underlying this association have not been fully demonstrated. Long noncoding RNAs (lncRNAs) are an intriguing class of widely prevalent endogenous RNAs involved in OS progre...

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Bibliographic Details

Published in:	Biology Direct
Main Authors:	Zhining Yang, Zhaoyong Liu, Weiqing Lu, Huancheng Guo, Jianzhou Chen, Ying Zhang
Format:	Article
Language:	English
Published:	BMC 2023-11-01
Subjects:	Osteosarcoma WAC-AS1 miR-5047 SOX2 Stemness
Online Access:	https://doi.org/10.1186/s13062-023-00433-2