The open field assay is influenced by room temperature and by drugs that affect core body temperature [version 3; peer review: 1 approved, 2 approved with reservations]
Background The open field assay is used to study anxiety-related traits and anxiolytic drugs in rodents. This assay entails measuring locomotor activity and time spent in the center of a chamber that is maintained at ambient room temperature. However, the ambient temperature in most laboratories var...
| Published in: | F1000Research |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2024-02-01
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| Subjects: | |
| Online Access: | https://f1000research.com/articles/12-234/v3 |