Cortical bone mechanical properties are altered in an animal model of progressive chronic kidney disease.

Chronic kidney disease (CKD), which leads tocortical bone loss and increasedporosity,increases therisk of fracture. Animal models have confirmed that these changes compromise whole bone mechanical properties. Estimates from whole bone testing suggest that material properties are negatively affected,...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Christopher L Newman, Sharon M Moe, Neal X Chen, Max A Hammond, Joseph M Wallace, Jeffry S Nyman, Matthew R Allen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Online Access:	http://europepmc.org/articles/PMC4049798?pdf=render