The effect of trimetazidine on cardiac haemodynamics and mitochondrial function in wild‐type transthyretin amyloidosis

Abstract Aims Wild‐type transthyretin cardiac amyloidosis (ATTRwt) is a cardiomyopathy causing myocardial hypoperfusion and impaired cardiac mitochondrial function. Trimetazidine is an antianginal agent used in patients with stable angina pectoris, which improves cardiac contractility and mitochondr...

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Bibliographic Details

Published in:	ESC Heart Failure
Main Authors:	Bertil Thyrsted Ladefoged, Anders Lehmann Dahl Pedersen, Anne Mette Dybro, Tor Skibsted Clemmensen, Julian Gillmore, Steen Hvitfeldt Poulsen
Format:	Article
Language:	English
Published:	Wiley 2025-06-01
Subjects:	cardiac amyloidosis high‐resolution respirometry invasive haemodynamics mitochondrial oxidative phosphorylation transthyretin amyloidosis trimetazidine
Online Access:	https://doi.org/10.1002/ehf2.15181