Photodynamic therapeutic activity of novel porphyrins against lung squamous cell carcinoma

Abstract Porphyrins, as drug-food homologous bioactive substances, hold significant potential in nanomedicine research and photodynamic therapy (PDT). In this study, we synthesized two novel porphyrin compounds, PTA and PTBA, based on the porphyrin compound TCPP. Using these compounds, we prepared m...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Hao Meng, Ren-Quan Ding, Lei Jia, Xiang-peng Chen, Yu-hang Hu, Shu-min Wang, Si-qi Lv, Fan Feng
Format:	Article
Language:	English
Published:	BMC 2025-05-01
Subjects:	Porphyrins Photodynamic therapy Porphyrin-metal nanoparticles Lung squamous lung cancer Antitumor activation
Online Access:	https://doi.org/10.1186/s12885-025-14386-4