Sex differences in peripheral and central dysregulation of the kynurenine pathway in Parkinson’s disease

Abstract We previously demonstrated that kynurenine pathway (KP) dysregulation associates with Parkinson’s disease (PD) and its symptoms. Here, we profiled 16 KP-related markers in a second, independent cohort; plasma: n = 202 (116 PD (“OFF”), 86 controls); CSF: n = 183 (108, 75). Consistent with pr...

詳細記述

書誌詳細

出版年:	npj Parkinson's Disease
主要な著者:	Leslie C. Jellen, Martha L. Escobar Galvis, Qiong Sha, Christine Isaguirre, Amy Johnson, Zach Madaj, Mechelle M. Lewis, Ryan D. Sheldon, Lan Kong, Xuemei Huang, Lena Brundin
フォーマット:	論文
言語:	英語
出版事項:	Nature Portfolio 2025-05-01
オンライン･アクセス:	https://doi.org/10.1038/s41531-025-00949-6