Sex differences in peripheral and central dysregulation of the kynurenine pathway in Parkinson’s disease

Abstract We previously demonstrated that kynurenine pathway (KP) dysregulation associates with Parkinson’s disease (PD) and its symptoms. Here, we profiled 16 KP-related markers in a second, independent cohort; plasma: n = 202 (116 PD (“OFF”), 86 controls); CSF: n = 183 (108, 75). Consistent with pr...

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發表在:npj Parkinson's Disease
Main Authors: Leslie C. Jellen, Martha L. Escobar Galvis, Qiong Sha, Christine Isaguirre, Amy Johnson, Zach Madaj, Mechelle M. Lewis, Ryan D. Sheldon, Lan Kong, Xuemei Huang, Lena Brundin
格式: Article
語言:英语
出版: Nature Portfolio 2025-05-01
在線閱讀:https://doi.org/10.1038/s41531-025-00949-6

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