Zika purified inactivated virus (ZPIV) vaccine reduced vertical transmission in pregnant immunocompetent mice

Abstract Zika virus (ZIKV) is a significant threat to pregnant women and their fetuses as it can cause severe birth defects and congenital neurodevelopmental disorders, referred to as congenital Zika syndrome (CZS). Thus, a safe and effective ZIKV vaccine for pregnant women to prevent in utero ZIKV...

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Bibliographic Details

Published in:	npj Vaccines
Main Authors:	In-Jeong Kim, Michael P. Tighe, Paula A. Lanthier, Madeline J. Clark, Rafael A. De La Barrera, Vincent Dussupt, Letzibeth Mendez-Rivera, Shelly J. Krebs, Kelsey L. Travis, Timothy C. Low-Beer, Tres S. Cookenham, Kathleen G. Lanzer, Derek T. Bernacki, Frank M. Szaba, Amanda A. Schneck, Jerrold Ward, Stephen J. Thomas, Kayvon Modjarrad, Marcia A. Blackman
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-02-01
Online Access:	https://doi.org/10.1038/s41541-024-00823-1