Directly infected resting CD4+T cells can produce HIV Gag without spreading infection in a model of HIV latency.

Despite the effectiveness of highly active antiretroviral therapy (HAART) in treating individuals infected with HIV, HAART is not a cure. A latent reservoir, composed mainly of resting CD4+T cells, drives viral rebound once therapy is stopped. Understanding the formation and maintenance of latently...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	PLoS Pathogens
المؤلفون الرئيسيون:	Matthew J Pace, Erin H Graf, Luis M Agosto, Angela M Mexas, Frances Male, Troy Brady, Frederic D Bushman, Una O'Doherty
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Public Library of Science (PLoS) 2012-01-01
الوصول للمادة أونلاين:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22911005/pdf/?tool=EBI