Colon adenocarcinoma and Birt–Hogg–Dubé syndrome in a young patient: case report and exploration of pathologic implications

Birt–Hogg–Dubé syndrome (BHD) is an autosomal dominant disorder caused by germline mutations in the folliculin gene (FLCN) that result in the functional loss of the tumor suppressor folliculin. It is classically associated with cutaneous hamartomas, pulmonary cysts with spontaneous pneumothorax, and...

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Bibliographic Details

Published in:	Cancer Biology & Therapy
Main Authors:	Grant W. Jirka, Daniel S. Lefler, Jessica Russo, Babar Bashir
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Subjects:	birt–hogg–dubé syndrome colorectal cancer folliculin gene flcn mutation wnt signaling
Online Access:	http://dx.doi.org/10.1080/15384047.2023.2184153