Feasibility of plant-expression system for production of recombinant anti-human IgE: An alternative production platform for therapeutic monoclonal antibodies

Omalizumab, the anti-immunoglobulin IgE antibody is the only approved and available monoclonal antibody as an auxiliary medicament for the severe respiratory allergic reactions. It forms small size immune complexes by binding to free IgE, thereby inhibiting the interaction of IgE with its receptors....

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Bibliographic Details

Published in:	Frontiers in Plant Science
Main Authors:	Oranicha Hanittinan, Kaewta Rattanapisit, Ashwini Malla, Kittipan Tharakhet, Chutitorn Ketloy, Eakachai Prompetchara, Waranyoo Phoolcharoen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Subjects:	asthma immunoglobulin E monoclonal antibody respiratory ailments recombinant proteins transient expression
Online Access:	https://www.frontiersin.org/articles/10.3389/fpls.2022.1012583/full