CIN grades possessing different HPV RNA location patterns and RNAscope is helpful tool for distinguishing squamous intraepithelial lesions in difficult cervical cases

Abstract Background and objectives The precise grading and characterization of cervical intraepithelial neoplasia (CIN) has been the focus of pathologists for a long time. This study aimed to explore known strategies for the grading of CINs. Methods After routine H&E review, 85 lesions graded CI...

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Bibliographic Details

Published in:	Diagnostic Pathology
Main Authors:	Ruichao Chen, Renchao Zhang, Minfen Zhang, Shaoyan Liu, Mingyu Xie, Zhongfeng Yang, Quan Shi, Hui Chen, Hanzhen Xiong, Na Wang, Qingping Jiang
Format:	Article
Language:	English
Published:	BMC 2023-02-01
Subjects:	Cervical intraepithelial neoplasia Human papilloma virus RNAscope
Online Access:	https://doi.org/10.1186/s13000-023-01308-w