Concurrent Inflammation Augments Antimalarial Drugs-Induced Liver Injury in Rats

Purpose: Accumulating evidence suggests that drug exposure during a modest inflammation induced by bacterial lipopolysaccharide (LPS) might increase the risk of drug-induced liver injury. The current investigation was designed to test if antimalarial drugs hepatotoxicity is augmented in LPS‑treated...

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Bibliographic Details

Published in:	Advanced Pharmaceutical Bulletin
Main Authors:	Hossein Niknahad, Reza Heidari, Roya Firuzi, Farzaneh Abazari, Maral Ramezani, Negar Azarpira, Massood Hosseinzadeh, Asma Najibi, Arastoo Saeedi
Format:	Article
Language:	English
Published:	Tabriz University of Medical Sciences 2016-12-01
Subjects:	Drug-Induced Liver Injury Hepatotoxicity Inflammation Lipopolysaccharide Malaria
Online Access:	http://journals.tbzmed.ac.ir/APB/Manuscript/APB-6-617.pdf