Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38‐Targeted Lipid Nanoparticles

Abstract Multiple myeloma (MM) is a cancer of differentiated plasma cells that occurs in the bone marrow (BM). Despite the recent advancements in drug development, most patients with MM eventually relapse and the disease remains incurable. RNA therapy delivered via lipid nanoparticles (LNPs) has the...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Dana Tarab‐Ravski, Inbal Hazan‐Halevy, Meir Goldsmith, Lior Stotsky‐Oterin, Dor Breier, Gonna Somu Naidu, Anjaiah Aitha, Yael Diesendruck, Brandon D. Ng, Hagit Barsheshet, Tamar Berger, Iuliana Vaxman, Pia Raanani, Dan Peer
Format:	Article
Language:	English
Published:	Wiley 2023-07-01
Subjects:	BM niche cancer lipid nanoparticles MM murine model multiple myeloma RNA therapy
Online Access:	https://doi.org/10.1002/advs.202301377