A novel highly potent therapeutic antibody neutralizes multiple human chemokines and mimics viral immune modulation.

Chemokines play a key role in leukocyte recruitment during inflammation and are implicated in the pathogenesis of a number of autoimmune diseases. As such, inhibiting chemokine signaling has been of keen interest for the development of therapeutic agents. This endeavor, however, has been hampered du...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Michelle L Scalley-Kim, Bruce W Hess, Ryan L Kelly, Anne-Rachel F Krostag, Kurt H Lustig, John S Marken, Pamela J Ovendale, Aaron R Posey, Pamela J Smolak, Janelle D L Taylor, C L Wood, David L Bienvenue, Peter Probst, Ruth A Salmon, Daniel S Allison, Teresa M Foy, Carol J Raport
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3422223?pdf=render