An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

Summary: Lymphatic endothelial cells (LECs) of the lymph node (LN) parenchyma orchestrate leukocyte trafficking and peripheral T cell dynamics. T cell responses to immunotherapy largely rely on peripheral T cell recruitment in tumors. Yet, a systematic and molecular understanding of how LECs within...

Full description

Bibliographic Details

Published in:	Cell Reports
Main Authors:	Diede Houbaert, Apostolos Panagiotis Nikolakopoulos, Kathryn A. Jacobs, Odeta Meçe, Jana Roels, Gautam Shankar, Madhur Agrawal, Sanket More, Maarten Ganne, Kristine Rillaerts, Louis Boon, Magdalena Swoboda, Max Nobis, Larissa Mourao, Francesca Bosisio, Niels Vandamme, Gabriele Bergers, Colinda L.G.J. Scheele, Patrizia Agostinis
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Subjects:	CP: Immunology CP: Cancer
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724003486