The potential key genes within focal adhesion that regulate mesenchymal stem cells osteogenesis or adipogenesis in microgravity related disuse osteoporosis: an integrated analysis

This study aimed to identify key genes related to focal adhesions (FA) and cells involved in osteoblast (OS) and adipocyte (AD) differentiation in osteoporosis. A mouse model of disuse osteoporosis was made by hindlimbs unloading (HLU)/Tail - suspension. Micro - CT and histological analysis were don...

Full description

Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Haoyang Zhao, Xiaolin Tu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	osteoporosis osteogenesis adipogenesis focal adhesions mesenchymal stem cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1469400/full