AuxB interacts directly with GpsB and PknB to coordinate cell envelope processes that contribute to intrinsic antibiotic resistance in Staphylococcus aureus

ABSTRACT Staphylococcus aureus, a leading cause of serious infections, produces various factors important for intrinsic resistance to antibiotics. Understanding what intrinsic resistance factors do may enable strategies to potentiate existing antibiotics. The membrane protein AuxB is an intrinsic re...

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Bibliographic Details

Published in:	mBio
Main Authors:	Tyler A. Sisley, Youngseon Park, Ace George Santiago, Wanassa Beroual, Isabella A. Sobolewski, Wonsik Lee, Joao A. Paulo, Suzanne Walker
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-10-01
Subjects:	serine/threonine kinases cell envelope cell wall Staphylococcus aureus antibiotic resistance PknB
Online Access:	https://journals.asm.org/doi/10.1128/mbio.01858-25