Molecular characterization of the salivary adenoid cystic carcinoma immune landscape by anatomic subsites

Abstract Adenoid cystic carcinoma (AdCC) is a slow-growing salivary gland malignancy that relapses frequently. AdCCs of the submandibular gland exhibit unique differences in prognosis and treatment response to adjuvant radiotherapy compared to other sites, yet the role of tumor anatomic subsite on g...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Jason Tasoulas, Travis P. Schrank, Harish Bharambe, Jay Mehta, Steven Johnson, Kimon Divaris, Trevor G. Hackman, Siddharth Sheth, Kedar Kirtane, Juan C. Hernandez-Prera, Christine H. Chung, Wendell G. Yarbrough, Renata Ferrarotto, Natalia Issaeva, Stamatios Theocharis, Antonio L. Amelio
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-07-01
Subjects:	Adenoid cystic carcinoma (AdCC) Salivary gland cancer (SGC) Tumor biology Tumor immune microenvironment (TIME)
Online Access:	https://doi.org/10.1038/s41598-024-66709-3