Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway

Kinsenoside (KD) exhibits anti-inflammatory and immunosuppressive effects. Dendritic cells (DCs) are critical regulators of the pathologic inflammatory milieu in liver fibrosis (LF). Herein, we explored whether and how KD repressed development of LF via DC regulation and verified the pathway involve...

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出版年:	Pharmacological Research
主要な著者:	Ming Xiang, Tingting Liu, Cheng Tian, Kun Ma, Jing Gou, Rongrong Huang, Senlin Li, Qing Li, Chuanrui Xu, Lei Li, Chih-Hao Lee, Yonghui Zhang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2022-03-01
主題:	Liver fibro-inflammation Kinsenoside Dendritic cell PI3K-AKT-FoxO1 axis Programmed cell death ligand 1 Interleukin-12
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S1043661822000378