Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans

Gene therapy (GT) using haematopoietic stem cells (HSCs) provides an opportunity to trace cell fates in humans, in vivo. Here the authors present evidence in GT patients for a long term lymphoid progenitor population, surviving and maintaining de novo T and NK cell production for years, independentl...

Full description

Bibliographic Details

Published in:	Nature Communications
Main Authors:	Natalia Izotova, Christine Rivat, Cristina Baricordi, Elena Blanco, Danilo Pellin, Eleanor Watt, Athina S. Gkazi, Stuart Adams, Kimberly Gilmour, Jinhua Bayford, Claire Booth, H. Bobby Gaspar, Adrian J. Thrasher, Luca Biasco
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-03-01
Online Access:	https://doi.org/10.1038/s41467-021-21834-9