Reciprocal regulation between alternative splicing and the DNA damage response

Abstract Splicing, the process that catalyzes intron removal and flanking exon ligation, can occur in different ways (alternative splicing) in immature RNAs transcribed from a single gene. In order to adapt to a particular context, cells modulate not only the quantity but also the quality (alternati...

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Bibliographic Details

Published in:	Genetics and Molecular Biology
Main Authors:	Adrian E. Cambindo Botto, Juan C. Muñoz, Luciana E. Giono, Nicolás Nieto-Moreno, Carmen Cuenca, Alberto R. Kornblihtt, Manuel J. Muñoz
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Genética 2020-03-01
Subjects:	DNA damage alternative splicing ATR ATM DNA-PK
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000200310&tlng=en