Repurposing of the Drug Tezosentan for Cancer Therapy
Tezosentan is a vasodilator drug that was originally developed to treat pulmonary arterial hypertension. It acts by inhibiting endothelin (ET) receptors, which are overexpressed in many types of cancer cells. Endothelin-1 (ET1) is a substance produced by the body that causes blood vessels to narrow....
| Published in: | Current Issues in Molecular Biology |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/1467-3045/45/6/325 |