EPS inhibitor treatment of Salmonella impacts evolution without selecting for resistance to biofilm inhibition

Abstract Virulence factors of pathogens, such as toxin production and biofilm formation, often exhibit a public character, providing benefits to nearby non-producers. Consequently, anti-virulence drugs targeting these public traits may not select for resistance, as resistant mutants that resume prod...

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Bibliographic Details

Published in:	npj Biofilms and Microbiomes
Main Authors:	Mathieu Joos, Sybren Van Ginneken, Xabier Villanueva, Marie Dijkmans, Guglielmo A. Coppola, Camilo Andres Pérez-Romero, Thijs Vackier, Erik Van der Eycken, Kathleen Marchal, Bram Lories, Hans P. Steenackers
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-05-01
Online Access:	https://doi.org/10.1038/s41522-025-00693-y