LEFTY2/endometrial bleeding-associated factor up-regulates Na+ Coupled Glucose Transporter SGLT1 expression and Glycogen Accumulation in Endometrial Cancer Cells.

LEFTY2 (endometrial bleeding associated factor; EBAF or LEFTYA), a cytokine released shortly before menstrual bleeding, is a negative regulator of cell proliferation and tumour growth. LEFTY2 down-regulates Na+/H+ exchanger activity with subsequent inhibition of glycolytic flux and lactate productio...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Ni Zeng, Toshiyuki Okumura, Md Alauddin, Shayan Khozooei, Janet Rajaxavier, Shaqiu Zhang, Yogesh Singh, Bing Shi, Sara Y Brucker, Diethelm Wallwiener, Satoru Takeda, Florian Lang, Madhuri S Salker
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2020-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0230044