Histological analysis of nucleus pulposus tissue from patients with lumbar disc herniation after condoliase administration

Abstract Background Condoliase is an enzyme used as a treatment for lumbar disc herniation (LDH). This enzyme degrades chondroitin sulfate (CS) in the nucleus pulposus of the intervertebral disc (IVD). However, there are cases in which symptoms do not improve, despite condoliase administration. This...

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Bibliographic Details

Published in:	JOR Spine
Main Authors:	Yuka Minamisawa, Taiichi Shirogane, Ippei Watanabe, Akira Dezawa
Format:	Article
Language:	English
Published:	Wiley 2024-06-01
Subjects:	chemonucleolysis chondroitin sulfate condoliase immunohistochemistry lumbar disc herniation
Online Access:	https://doi.org/10.1002/jsp2.1328