The impact of S2 mutations on Omicron SARS-CoV-2 cell surface expression and fusogenicity

SARS-CoV-2 Omicron subvariants are still emerging and spreading worldwide. These variants contain a high number of polymorphisms in the spike (S) glycoprotein that could potentially impact their pathogenicity and transmission. We have previously shown that the S:655Y and P681H mutations enhance S pr...

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Bibliographic Details

Published in:	Emerging Microbes and Infections
Main Authors:	Alba Escalera, Manon Laporte, Sam Turner, Umut Karakus, Ana S. Gonzalez-Reiche, Adriana van de Guchte, Keith Farrugia, Zain Khalil, Harm van Bakel, Derek Smith, Adolfo García-Sastre, Teresa Aydillo
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Subjects:	SARS-CoV-2 Omicron spike cell–cell fusion spike cell surface expression “first-generation” Omicron sublineages
Online Access:	https://www.tandfonline.com/doi/10.1080/22221751.2023.2297553