A Retrospective Analysis of Rituximab Treatment for B Cell Depletion in Different Pediatric Indications

Background: Rituximab (RTX) is used in cancer therapy as well as in the treatment of autoimmune diseases and alloimmune responses after transplantation. It depletes the disease-causing B cells by binding to the CD (cluster of differentiation) 20 antigen. We evaluate different pediatric treatment pro...

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Bibliographic Details
Published in:Frontiers in Pediatrics
Main Authors: Merlin Wennmann, Simone Kathemann, Kristina Kampmann, Sinja Ohlsson, Anja Büscher, Dirk Holzinger, Adela Della Marina, Elke Lainka
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Subjects:
rituximab
B cell depletion
hypogammaglobulinaemia
immunodeficiency
antibody
pediatric
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.651323/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2021.651323/full

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