H2A.Z deposition by the SWR complex is stimulated by polyadenine DNA sequences in nucleosomes.

The variant histone H2A.Z is deposited into nucleosomes immediately downstream of promoters, where it plays a critical role in transcription. The site-specific deposition of H2A.Z is catalyzed by the SWR complex, a conserved chromatin remodeler with affinity for promoter-proximal nucleosome-depleted...

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Bibliographic Details

Published in:	PLoS Biology
Main Authors:	Cynthia Converso, Leonidas Pierrakeas, Lirong Chan, Shalvi Chowdhury, Emily de Onis, Vyacheslav I Kuznetsov, John M Denu, Ed Luk
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-05-01
Online Access:	https://doi.org/10.1371/journal.pbio.3003059